It is not known if ACIPHEX can be safe and effective if used longer than 12 months .For 4 weeks to take care of daytime and nighttime heartburn and additional symptoms that happen with Gastroesophageal Reflux Disease .GERD happens when acid in your belly backs up into the tube that connects your mouth to your stomach. This might cause a burning sense in your upper body or throat, sour flavor, or burping.for 4 weeks for the healing and comfort of duodenal ulcers. The duodenal area is the certain area where food passes when it leaves the stomach. Side effect: Diarrhea. ACIPHEX might increase your risk of getting severe diarrhea. This diarrhea may be caused by an infection in your intestines. Call your doctor right away for those who have watery stool, stomach pain, and fever that will not go away.Laparoscopic medical procedures for acid reflux involves strengthening that natural barrier by wrapping section of the belly around the lower area of the esophagus. In the analysis which was executed at University Hospital, Angers, France, the sufferers were followed on average for a lot more than seven years following the surgery. Although almost ten % of the individuals resumed taking heartburn medicine, in most no evidence of reflux recurrence could possibly be found.