These findings give us a fresh perspective from which to develop better strategies for avoidance and therapy. This research was backed by the National Institute on Drug Abuse.. Abuse of painkillers can predispose adolescents to lifelong addiction No child aspires to a lifetime of addiction. But their brains may. Today In new research to appear online in the journal Neuropsychopharmacology, Rockefeller University researchers reveal that adolescent brains exposed to the painkiller OxyContin can sustain lifelong and long lasting changes in their reward system – adjustments that increase the drug’s euphoric properties and make such adolescents even more susceptible to the drug’s effects later in adulthood.Both genetic tests are called chromosomal microarray analysis and whole-exome sequencing. ‘They are two very comprehensive tests that haven’t been with us for too much time,’ Fernandez said. Chromosomal microarray analysis identifies abnormalities in someone’s chromosomes, and already is recommended as a first-tier genetic test for people with autism, the researchers said in background notes. Whole-exome sequencing examines the protein-encoding elements of most of someone’s genes, to look for potential disease-causing anomalies.